What Are the Symptoms of Stiff Person Syndrome?

Stiff person syndrome is a rare neurological disorder that causes muscle stiffness and spasms. Find out more about diagnosis and treatment options.

By Jake Parks; Medically Reviewed by Dr. Ahmad Talha Azam
Feb 28, 2024 8:00 PM
woman sitting on couch holding lower back from back pain
(Creidt: Povozniuk/Getty Images)

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Stiff Person Syndrome (SPS) is a rare autoimmune neurological condition that has puzzled the medical community for years. Affecting a small percentage of the population, SPS leads to a variety of symptoms, primarily muscle stiffness and spasms, which cause significant discomfort and challenges.

In this article, we’ll dive into what SPS is, its symptoms, causes, how it’s diagnosed, and treatment options, giving you an in depth understanding of this highly complex condition.

Remember, be sure to speak with a qualified medical professional if you are experiencing any unusual health issues that are causing you concern.

What Is Stiff Person Syndrome?

Stiff Person Syndrome is characterized by increased muscle stiffness and spasms, predominantly affecting the trunk, spinal muscles, and limbs. Symptoms of SPS can vary from mild to debilitating and typically progress over time, often leading to severe physical and psychological challenges, as well as impacting the mobility and the quality of life of those affected.

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