No, GM Mosquitoes Didn't Start The Zika Outbreak.

Science Sushi
By Christie Wilcox
Feb 1, 2016 8:56 AMNov 19, 2019 8:20 PM
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A new ridiculous rumor is spreading around the internets. According to conspiracy theorists, the recent outbreak of Zika can be blamed on the British biotech company Oxitec, which some are saying even intentionally caused the disease as a form of ethnic cleansing or population control. The articles all cite a lone Redditor who proposed the connection on January 25th to the Conspiracy subreddit. "There are no biological free lunches," says one commenter on the idea. "Releasing genetically altered species into the environment could have disastrous consequences" another added. "Maybe that's what some entities want to happen...?" For some reason, it's been one of those months where random nonsense suddenly hits mainstream. Here are the facts: there's no evidence whatsoever to support this conspiracy theory, or any of the other bizarre, anti-science claims that have popped up in the past few weeks. So let's stop all of this right here, right now: The Earth is round, not flat (and it's definitely not hollow). Last year was the hottest year on record, and climate change is really happening (so please just stop, Mr. Cruz). And FFS, genetically modified mosquitoes didn't start the Zika outbreak. Background on Zika The Zika virus is a flavivirus closely related to notorious pathogens including dengue, yellow fever, Japanese encephalitis, and West Nile virus. The virus is transmitted by mosquitoes in the genus Aedes, especially A. aegypti, which is a known vector for many of Zika's relatives. Symptoms of the infection appear three to twelve days post bite. Most people are asymptomatic, which means they show no signs of infection. The vast majority of those who do show signs of infection report fever, rash, joint pain, and conjunctivitis (red eyes), according to the U.S. Centers for Disease Control. After a week or less, the symptoms tend to go away on their own. Serious complications have occurred, but they have been extremely rare. The Zika virus isn't new. It was first isolated in 1947 from a Rhesus monkey in the Zika Forest in Uganda, hence the pathogen's name. The first human cases were confirmed in Uganda and Tanzania in 1952, and by 1968, the virus had spread to Nigeria. But since then, the virus has found its way out of Africa. The first major outbreak occurred on the island of Yap in Micronesia for 13 weeks 2007, during which 185 Zika cases were suspected (49 of those were confirmed, with another 59 considered probable). Then, in October 2013, an outbreak began in French Polynesia; around 10,000 cases were reported, less than 100 of which presented with severe neurological or autoimmune complications. One confirmed case of autochthonous transmission occurred in Chile in 2014, which means a person was infected while they were in Chile rather than somewhere else. Cases were also reported that year from several Pacific Islands. The virus was detected in Chile until June 2014, but then it seemed to disappear. Fast forward to May 2015, when the Pan American Health Organization (PAHO) issued an alert regarding the first confirmed Zika virus infection in Brazil. Since then, several thousand suspected cases of the disease and a previously unknown complication—a kind of birth defect known as microcephaly where the baby's brain is abnormally small—have been reported from Brazil. (It's important to note that while the connection between the virus and microcephaly is strongly suspected, the link has yet to be conclusively demonstrated.) Currently, there is no vaccine for Zika, though the recent rise in cases has spurred research efforts. Thus, preventing mosquito bites is the only prophylactic measure available. The recent spread of the virus has been described as "explosive"; Zika has now been detected in 25 countries and territories. The rising concern over both the number of cases and reports of serious complications has led the most affected areas in Brazil to declare a state of emergency, and on Monday, The World Health Organization's Director-General will convene an International Health Regulations Emergency Committee on Zika virus and the observed increase in neurological disorders and neonatal malformations. At this emergency meeting, the committee will discuss mitigation strategies and decide whether the organization will officially declare the virus a "Public Health Emergency of International Concern." GM to the Rescue

Aedes aegypti: the invasive mosquito in Brazil that carries Zika virus and other awful diseases. Photo by James Gathany, c/o the CDC The mosquito to blame for the outbreak—Aedes aegypti—doesn't belong in the Americas. It's native to Africa, and was only introduced in the new world when Europeans began to explore the globe. In the 20th century, mosquito control programs nearly eradicated the unwelcome menace from the Americas (largely thanks to the use of the controversial pesticide DDT); as late as the mid 1970s, Brazil and 15 other nations were Aedes aegypti-free. But despite the successes, eradication efforts were halted, allowing the mosquito to regain its lost territory.

The distribution of Aedes aegypti in the Americas in 1970 and 2002, from the Centers for Disease Control Effective control measures are expensive and difficult to maintain, so at the tail end of the 20th century and into the 21st, scientists began to explore creative means of controlling mosquito populations, including the use of genetic modification. Oxitec's mosquitoes are one of the most exciting technologies to have emerged from this period. Here's how they work, as I described in a post almost exactly a year ago:

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