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Chemical in Predator Pee Scares the Pee Out of Rodents

Discover how chemical cues in predator-prey interactions help rodents avoid danger from predators. Explore research on 2-phenylethylamine.

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What’s the News: In the animal kingdom, prey species must follow one rule above all others: keep away from predators. To do this, some animals take chemical cues from the urine they stumble upon. Now, new research

published in the Proceedings of the National Academy of Science has identified a single molecule in the urine of many mammalian carnivores that causes rodents to scurry in fear. This chemical could eventually help scientists understand instinctual behavior in animals. How the Heck:

A research team at the Harvard Medical School analyzed a group of olfactory receptors called trace amine-associated receptors (TAARs). They concentrated on one in particular, TAAR4, which is strongly activated by bobcat urine (sometimes used by gardeners to repel small pests). They found that one specific molecule, called 2-phenylethylamine, is responsible for the TAAR4 reaction.

To see if 2-phenylethylamine is bobcat specific, the team tested urine samples from 38 mammalian ...

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