Groundbreaking Brain Atlas Maps Whole Brain at Cellular Level

D-brief
By Becky Lang
Jun 20, 2013 10:03 PMDec 19, 2019 6:30 PM
brainatlas.jpg
A frame of the BigBrain reference model. (Credit: Montreal Neurological Institute/McGill University, Institute of Neuroscience and Medicine/Research Centre Julich, and National Research Council of Canada)

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Researchers have for the first time built a 3D model of a human brain showing structural detail down to the cellular level. This ultra high-resolution atlas, dubbed “BigBrain,” aims to show the architecture of the brain at various levels — from the cortex’s layers and columns to its microcircuits and cells.

Researchers use a special tool called a microtome to cut sections from a brain preserved in paraffin wax. (Courtesy of Amunts, Zilles, Evans et al.)
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