How 8 Supplements Like Vitamin D and Omega-3 Interact with Medication

Learn why certain supplements taken with common medication can impact the body. Be sure to double check with your doctor before taking these supplements.

By Allison Futterman; Medically Reviewed by Dr. Ahmad Talha Azam
Feb 16, 2024 4:00 PM
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(Credit: ULV/Shutterstock)

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Harmful effects from supplements account for approximately 23,000 emergency room (ER) visits each year, while adverse medication reactions result in 1.3 million ER visits annually.

And if supplements and certain medications are taken together, they can also cause a negative reactions. The side effects range widely from increasing or decreasing the medicinal effect or causing a toxic reaction. While it's always important to consult a doctor before using medication, here are some examples of supplement and medication combinations that could cause health issues.

1. Omega-3

Omega-3 fatty acids, most commonly found in fish oil supplements, are used to mitigate heart disease, high blood pressure, and triglyceride reduction.

How Does Omega-3 Interfere With Medication?

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