Neural rainbow

Individual neurons in the mouse brain show up differently colored in this "Brainbow"-labeled sample of a cerebral cortex. Brainbow is the process of labeling neurons with fluorescent protein to distinguish them and follow their paths through brain tissue.

The neurons shown here are pyramidal neurons, so called because of their triangle-shaped cell bodies. The image was taken with multiphoton microscopy with wavelength mixing, and it received an Honorable Mention in the 2012 Olympus BioScapes Digital Imaging Competition.

Pierre Mahou and Emmanuel Beaurepaire, Laboratory for Optics and Biosciences, Ecole Polytechnique, Palaiseau, France, and Karine Loulier, Institut de la Vision, Paris, France