When Americans imagine an epidemic, they are most likely to think of HIV. But as the dark red swath on the map above shows, in much of the world an equally formidable foe is tuberculosis, a bacterial disease characteristically concentrated in the lungs. Globally, the burden of disease from TB in 2010 ranked 13th overall, ahead of drug use, suicide, diabetes or any kind of cancer. In Southeast Asia, TB was second only to strokes. Based in part on an early global burden analysis, The Global Fund to Fight AIDS, Tuberculosis and Malaria was started in 2002.