End of Ascent

By Kathy A. Svitil|Tuesday, May 01, 2001

Have humans hit an evolutionary glass ceiling? According to Morris Goodman, a molecular evolutionist at Wayne State University in Detroit, we may have attained better brain power by accepting slower genetic change— a trade-off that leaves less room for mutations, both beneficial and deleterious.

Goodman and his colleagues analyzed snippets of noncoding DNA— parts of the genetic code that are not influenced by natural selection— in more than three dozen primate species. The researchers found a dramatic decrease in mutation rates along the evolutionary line leading to humans. The speed of mutation is systematically lower in species with more brainpower. Primates with the biggest brains and longest life spans, including chimps and humans, exhibited the slowest rates of all. Slowing the rate of change in the DNA, he says, means "more years elapse before the accumulation of mutations causes a cascade of cell deaths." In other words, putting the brakes on mutations may be the key to having a big brain and a sufficiently long life span to make good use of that intelligence.

Even so, Goodman remains optimistic that there is still room for human progress. Unlike other organisms, he says, we can respond culturally to environmental challenges, developing behavioral adaptations that, like genes, can be passed on from one generation to the next. "And if we ever decide to colonize Mars, the environment up there could initiate some new changes in biological evolution," Goodman says. "I think it is a mistake to think that evolution has ceased."

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